ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Home
About
List

Prostaglandin D2 receptor 2

Intramolecular
Cysteine 11 and cysteine 199
Cysteine 104 and cysteine 182
A redox-regulated disulphide may form within Prostaglandin D2 receptor 2 between cysteines 11 and 199.

Details

Redox score ?
85
PDB code
6d27
Structure name
crystal structure of the prostaglandin d2 receptor crth2 with cay10471
Structure deposition date
2018-04-13
Thiol separation (Å)
2
Half-sphere exposure sum ?
65
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9Y5Y4
Residue number A
11
Residue number B
199
Peptide name
Prostaglandin D2 receptor 2

Ligandability

Cysteine 11 of Prostaglandin D2 receptor 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 199 of Prostaglandin D2 receptor 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Prostaglandin D2 receptor 2 between cysteines 104 and 182.

Details

Redox score ?
84
PDB code
6d27
Structure name
crystal structure of the prostaglandin d2 receptor crth2 with cay10471
Structure deposition date
2018-04-13
Thiol separation (Å)
2
Half-sphere exposure sum ?
66
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9Y5Y4
Residue number A
104
Residue number B
182
Peptide name
Prostaglandin D2 receptor 2

Ligandability

Cysteine 104 of Prostaglandin D2 receptor 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 182 of Prostaglandin D2 receptor 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

If this tool was useful for finding a disulphide, please cite: