ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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Glucocorticoid modulatory element-binding protein 1

Intramolecular
Cysteine 174 and cysteine 178
Cysteine 113 and cysteine 178
Cysteine 113 and cysteine 174
A redox-regulated disulphide may form within Glucocorticoid modulatory element-binding protein 1 between cysteines 174 and 178.

Details

Redox score ?
93
PDB code
1oqj
Structure name
crystal structure of the sand domain from glucocorticoid modulatory element binding protein-1 (gmeb1)
Structure deposition date
2003-03-10
Thiol separation (Å)
4
Half-sphere exposure sum ?
nan
Minimum pKa ?
6
% buried
0
Peptide accession
Q9Y692
Residue number A
174
Residue number B
178
Peptide name
Glucocorticoid modulatory element-binding protein 1

Ligandability

Cysteine 174 of Glucocorticoid modulatory element-binding protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 178 of Glucocorticoid modulatory element-binding protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Glucocorticoid modulatory element-binding protein 1 between cysteines 113 and 178.

Details

Redox score ?
88
PDB code
1oqj
Structure name
crystal structure of the sand domain from glucocorticoid modulatory element binding protein-1 (gmeb1)
Structure deposition date
2003-03-10
Thiol separation (Å)
4
Half-sphere exposure sum ?
nan
Minimum pKa ?
7
% buried
1
Peptide accession
Q9Y692
Residue number A
113
Residue number B
178
Peptide name
Glucocorticoid modulatory element-binding protein 1

Ligandability

Cysteine 113 of Glucocorticoid modulatory element-binding protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 178 of Glucocorticoid modulatory element-binding protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Glucocorticoid modulatory element-binding protein 1 between cysteines 113 and 174.

Details

Redox score ?
87
PDB code
1oqj
Structure name
crystal structure of the sand domain from glucocorticoid modulatory element binding protein-1 (gmeb1)
Structure deposition date
2003-03-10
Thiol separation (Å)
4
Half-sphere exposure sum ?
47
Minimum pKa ?
6
% buried
4
Peptide accession
Q9Y692
Residue number A
113
Residue number B
174
Peptide name
Glucocorticoid modulatory element-binding protein 1

Ligandability

Cysteine 113 of Glucocorticoid modulatory element-binding protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 174 of Glucocorticoid modulatory element-binding protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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