ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Home
About
List

Testis-specific chromodomain protein Y 1

Intramolecular
Cysteine 342 and cysteine 343
Cysteine 427 and cysteine 513
A redox-regulated disulphide may form within Testis-specific chromodomain protein Y 1 between cysteines 342 and 343. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
51
PDB code
2fbm
Structure name
acetyltransferase domain of cdy1
Structure deposition date
2005-12-09
Thiol separation (Å)
6
Half-sphere exposure sum ?
81
Minimum pKa ?
11
% buried
82
Peptide accession
Q9Y6F8
Residue number A
342
Residue number B
343
Peptide name
Testis-specific chromodomain protein Y 1

Ligandability

Cysteine 342 of Testis-specific chromodomain protein Y 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 343 of Testis-specific chromodomain protein Y 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Testis-specific chromodomain protein Y 1 between cysteines 427 and 513. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
34
PDB code
2fbm
Structure name
acetyltransferase domain of cdy1
Structure deposition date
2005-12-09
Thiol separation (Å)
8
Half-sphere exposure sum ?
81
Minimum pKa ?
12
% buried
88
Peptide accession
Q9Y6F8
Residue number A
427
Residue number B
513
Peptide name
Testis-specific chromodomain protein Y 1

Ligandability

Cysteine 427 of Testis-specific chromodomain protein Y 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 513 of Testis-specific chromodomain protein Y 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

If this tool was useful for finding a disulphide, please cite: