Numb-like protein
Intramolecular
Cysteine 171 and cysteine 173
Cysteine 99 and cysteine 171
Cysteine 99 and cysteine 173
Cysteine 78 and cysteine 190
Cysteine 161 and cysteine 171
Cysteine 99 and cysteine 147
Cysteine 147 and cysteine 190
3f0w A 171 A 173
A redox-regulated disulphide may form within Numb-like protein between cysteines 171 and 173.
Details
Redox score ?
69
PDB code
3f0w
Structure name
human numb-like protein, phosphotyrosine interaction domain
Structure deposition date
2008-10-27
Thiol separation (Å)
4
Half-sphere exposure sum ?
84
Minimum pKa ?
9
% buried
79
Peptide accession
Q9Y6R0
Residue number A
171
Residue number B
173
Peptide name
Numb-like protein
Ligandability
Cysteine 171 of Numb-like protein
Cysteine 173 of Numb-like protein
3f0w A 99 A 171
A redox-regulated disulphide may form within Numb-like protein between cysteines 99 and 171.
Details
Redox score ?
62
PDB code
3f0w
Structure name
human numb-like protein, phosphotyrosine interaction domain
Structure deposition date
2008-10-27
Thiol separation (Å)
4
Half-sphere exposure sum ?
80
Minimum pKa ?
13
% buried
78
Peptide accession
Q9Y6R0
Residue number A
99
Residue number B
171
Peptide name
Numb-like protein
Ligandability
Cysteine 99 of Numb-like protein
Cysteine 171 of Numb-like protein
3f0w A 99 A 173
A redox-regulated disulphide may form within Numb-like protein between cysteines 99 and 173. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
53
PDB code
3f0w
Structure name
human numb-like protein, phosphotyrosine interaction domain
Structure deposition date
2008-10-27
Thiol separation (Å)
7
Half-sphere exposure sum ?
82
Minimum pKa ?
9
% buried
78
Peptide accession
Q9Y6R0
Residue number A
99
Residue number B
173
Peptide name
Numb-like protein
Ligandability
Cysteine 99 of Numb-like protein
Cysteine 173 of Numb-like protein
3f0w A 78 A 190
A redox-regulated disulphide may form within Numb-like protein between cysteines 78 and 190. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
42
PDB code
3f0w
Structure name
human numb-like protein, phosphotyrosine interaction domain
Structure deposition date
2008-10-27
Thiol separation (Å)
8
Half-sphere exposure sum ?
70
Minimum pKa ?
11
% buried
60
Peptide accession
Q9Y6R0
Residue number A
78
Residue number B
190
Peptide name
Numb-like protein
Ligandability
Cysteine 78 of Numb-like protein
Cysteine 190 of Numb-like protein
3f0w A 161 A 171
A redox-regulated disulphide may form within Numb-like protein between cysteines 161 and 171. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
41
PDB code
3f0w
Structure name
human numb-like protein, phosphotyrosine interaction domain
Structure deposition date
2008-10-27
Thiol separation (Å)
8
Half-sphere exposure sum ?
77
Minimum pKa ?
11
% buried
67
Peptide accession
Q9Y6R0
Residue number A
161
Residue number B
171
Peptide name
Numb-like protein
Ligandability
Cysteine 161 of Numb-like protein
Cysteine 171 of Numb-like protein
3f0w A 99 A 147
A redox-regulated disulphide may form within Numb-like protein between cysteines 99 and 147. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
41
PDB code
3f0w
Structure name
human numb-like protein, phosphotyrosine interaction domain
Structure deposition date
2008-10-27
Thiol separation (Å)
8
Half-sphere exposure sum ?
81
Minimum pKa ?
12
% buried
89
Peptide accession
Q9Y6R0
Residue number A
99
Residue number B
147
Peptide name
Numb-like protein
Ligandability
Cysteine 99 of Numb-like protein
Cysteine 147 of Numb-like protein
3f0w A 147 A 190
A redox-regulated disulphide may form within Numb-like protein between cysteines 147 and 190. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
29
PDB code
3f0w
Structure name
human numb-like protein, phosphotyrosine interaction domain
Structure deposition date
2008-10-27
Thiol separation (Å)
10
Half-sphere exposure sum ?
82
Minimum pKa ?
11
% buried
80
Peptide accession
Q9Y6R0
Residue number A
147
Residue number B
190
Peptide name
Numb-like protein
Ligandability
Cysteine 147 of Numb-like protein
Cysteine 190 of Numb-like protein
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