ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Home
About
List

Epididymis luminal protein 213

Intramolecular
Cysteine 43 and cysteine 109
Cysteine 155 and cysteine 215
A redox-regulated disulphide may form within Epididymis luminal protein 213 between cysteines 43 and 109 (23 and 88 respectively in this structure).

Details

Redox score ?
80
PDB code
6dkj
Structure name
human gipr ecd and fab complex
Structure deposition date
2018-05-29
Thiol separation (Å)
2
Half-sphere exposure sum ?
91
Minimum pKa ?
nan
% buried
nan
Peptide accession
V9HW34
Residue number A
43
Residue number B
109
Peptide name
Epididymis luminal protein 213

Ligandability

Cysteine 43 of Epididymis luminal protein 213

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 109 of Epididymis luminal protein 213

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Epididymis luminal protein 213 between cysteines 155 and 215 (134 and 194 respectively in this structure).

Details

Redox score ?
79
PDB code
6dkj
Structure name
human gipr ecd and fab complex
Structure deposition date
2018-05-29
Thiol separation (Å)
2
Half-sphere exposure sum ?
87
Minimum pKa ?
nan
% buried
nan
Peptide accession
V9HW34
Residue number A
155
Residue number B
215
Peptide name
Epididymis luminal protein 213

Ligandability

Cysteine 155 of Epididymis luminal protein 213

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 215 of Epididymis luminal protein 213

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

If this tool was useful for finding a disulphide, please cite: